The standing instructions that run on every generation, plus the approved-asset library the engine retrieves from. Edit the brand brain here and every variant in flight learns the new rule.
Voice rules · active
47
12 Compound DT-204-specific
Enforced on every generation
Approved assets
1,240
+86 this month
Photo · b-roll · logo · ISI variant
ISI variants
47
Auto-injected by audience
Long · short · pediatric · pregnancy
Forbidden phrases
184
OPDP + KNSA-internal
Auto-blocked in generation
Brand voice · standing instructions
The rules every generation follows
Encoded once, enforced on every brief. Add a rule here and every variant in flight re-validates against it. Top-25%/bottom-25% performance signal feeds back so the rules tune over time.
✓ Do
Use the full brand name 'Compound DT-204' on first reference; 'rilonacept' on second reference if scientific context.
Reference the indication explicitly: 'rare cardiology indication,' 'cardiac sarcoidosis,' 'CAPS,' 'DIRA' — not 'inflammatory diseases.'
Cite RHAPSODY trial when efficacy claims appear — pull exact stat + footnote text from the approved claims library.
Use named team voice ('our team', 'the medical team') or named-physician voice when patients/caregivers narrate.
Cost-and-access content names the Co-Pay program by its proper name and links to the Patient Assistance Foundation for government insurance.
Adverbs that imply superiority: 'fastest', 'most effective', 'leading'.
Off-label suggestions — efficacy mentions tie to FDA-approved indication only.
Disease-state pivot to branded claim without ISI proximity (≤ 2 lines or adjacent frame).
Consumer-influencer language: 'obsessed', 'spilling', 'the tea', 'glow-up', 'must-have'.
Emoji density above 3 per asset — degrades performance across all audiences (data-backed: −8× engagement vs no-emoji).
Approved asset library
Photography · b-roll · logos · diagrams
MLR-cleared, model-released, contractually-cleared. The engine pulls from this library when generating any visual format — never grabs stock or external imagery without explicit override.
Hero photography · patient142
Approved patient photography, model release on file. Ages 35–65, diverse ethnicities, indoor/outdoor variants.
Important Safety Information · auto-injected by audience
Every approved ISI variant — long-form, short-form, pediatric, audio-spec, channel-specific. The engine selects the right ISI for each output automatically based on audience profile + format.
Variant
Chars
Used in
Last review
Long-form · adult patient
2100
Patient sitePatient eBlastLong-form social
Q1 2026
Short-form · adult patient
480
Email bannerDisplay bannerCarousel last frame
Q1 2026
Long-form · HCP
2840
HCP eBlastDetail aidLinkedIn long-form
Q1 2026
Pediatric · caregiver-facing
1620
Pediatric campaignsParent-facing pages
Q1 2026
Audio-only · 60s spec
240
YouTube TrueViewPodcast pre-roll
Q4 2025
Reddit · community thread compatible
320
Reddit promoted postReddit conversation ad
Q1 2026
Cardiac sarcoidosis · adult patient
2180
CS-specific patient content
Q1 2026
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